ANATOMY

Detailed explanation-1: -The epicardium is the outermost layer of the heart. It is actually the visceral layer of the serous pericardium, which adheres to the myocardium of the heart. Histologically, it is made of mesothelial cells, the same as the parietal pericardium.

Detailed explanation-2: -The outer layer of the heart wall is the epicardium, the middle layer is the myocardium, and the inner layer is the endocardium.

Detailed explanation-3: -The epicardium is an evolutionarily conserved layer of mesothelium covering the outermost cell layer of the vertebrate heart. During fetal development, the epicardium serves as a progenitor source, contributing multipotent cells that give rise to cardiac mesenchyme.

Detailed explanation-4: -The visceral serous pericardium, also known as the epicardium, covers the myocardium of the heart and can be considered its serosa.

Detailed explanation-5: -The part of the visceral layer that covers the heart, but not the great vessels is called the epicardium. As the serous pericardium reflects off various cardiac structures, it forms two sinuses: the transverse sinus and the oblique sinus.