ANATOMY

Detailed explanation-1: -Hemostasis is the mechanism that leads to cessation of bleeding from a blood vessel. It is a process that involves multiple interlinked steps. This cascade culminates into the formation of a “plug” that closes up the damaged site of the blood vessel controlling the bleeding.

Detailed explanation-2: -Hemostasis is the physiological process by which bleeding ceases. Hemostasis involves three basic steps: vascular spasm, the formation of a platelet plug, and coagulation, in which clotting factors promote the formation of a fibrin clot.

Detailed explanation-3: -The mechanism of hemostasis can divide into four stages. 1) Constriction of the blood vessel. 2) Formation of a temporary “platelet plug.” 3) Activation of the coagulation cascade. 4) Formation of “fibrin plug” or the final clot.

Detailed explanation-4: -Platelet plug formation, also known as primary hemostasis, is the first step of hemostasis and is the process where a platelet plug forms to prevent further loss of blood from a damaged vessel. It is divided into five stages: endothelial injury, exposure, adhesion, activation, and aggregation.

Detailed explanation-5: -Vasoconstriction phase. Primary hemostasis is characterized by vasoconstriction, which is the initial phase for stopping the blood flow10. Vascular spasm occurs whenever there is an injury or damage to the blood vessels. This will trigger a vasoconstriction, which could eventually stop the blood flow.