ANATOMY

Detailed explanation-1: -Atherosclerosis is the buildup of fats, cholesterol and other substances in and on the artery walls. This buildup is called plaque. The plaque can cause arteries to narrow, blocking blood flow. The plaque can also burst, leading to a blood clot.

Detailed explanation-2: -Atherosclerosis is thickening or hardening of the arteries caused by a buildup of plaque in the inner lining of an artery. Risk factors may include high cholesterol and triglyceride levels, high blood pressure, smoking, diabetes, obesity, physical activity, and eating saturated fats.

Detailed explanation-3: -Atherosclerosis is a common condition that develops when a sticky substance called plaque builds up inside your artery. Disease linked to atherosclerosis is the leading cause of death in the United States.

Detailed explanation-4: -High blood pressure: Over time, high blood pressure can damage artery walls, allowing plaque to build up. Diabetes: High blood sugar can damage the inner layers of the arteries, causing plaque buildup. Metabolic syndrome: High levels of cholesterol and triglycerides in your blood increase your risk.

Detailed explanation-5: -High serum lipid levels, especially the elevated level of low-density lipoprotein (LDL), have been shown to be strongly related to the development of atherosclerosis. It is generally accepted that atherosclerotic lesions are initiated via an enhancement of LDL uptake by monocytes and macrophages.