ANATOMY

Detailed explanation-1: -The epicardium, or the innermost layer of the pericardium, is the outermost layer of the heart itself. It is composed of mesothelial cells, fat, and connective tissue. It is adjacent to the myocardium, the middle muscular layer.

Detailed explanation-2: -The epicardium is the outermost layer of the heart. It is actually the visceral layer of the serous pericardium, which adheres to the myocardium of the heart. Histologically, it is made of mesothelial cells, the same as the parietal pericardium.

Detailed explanation-3: -Endocardium. The inner layer of the heart wall is the endocardium, composed of endothelial cells that provide a smooth, elastic, non-adherent surface for blood collection and pumping.

Detailed explanation-4: -The wall of the heart separates into the following layers: epicardium, myocardium, and endocardium. These three layers of the heart are embryologically equivalent to the three layers of blood vessels: tunica adventitia, tunica media, and tunica intima, respectively.

Detailed explanation-5: -The visceral serous pericardium, also known as the epicardium, covers the myocardium of the heart and can be considered its serosa.