ANATOMY

Detailed explanation-1: -The muscles of the heart, termed the myocardium, make up the middle and thickest layer of the heart wall. This layer lies between the single-cell endocardium layer, which lines the inner chambers, and the outer epicardium, which makes up part of the pericardium that surrounds and protects the heart.

Detailed explanation-2: -The myocardium is functionally the main constituent of the heart and the thickest layer of all three heart layers. It is a muscle layer that enables heart contractions.

Detailed explanation-3: -The myocardium of the left ventricle is normally thicker than the rest of the heart. This is due to the fact that the left ventricle pumps blood into the systemic circulation, which necessitates a stronger contraction.

Detailed explanation-4: -The endocardium connects to blood vessels that supply the heart muscle and contributes to the regulation of heart contractions. The myocardium is the thickest layer of the heart wall, which is made up of myocytes, or cardiac muscle cells.

Detailed explanation-5: -The myocardium is mainly made up of two types of cells: cardiomyocytes and fibroblasts. Fibroblasts are distributed between cardiomyocytes, along with extracellular matrix (ECM), blood vessels, lymphatic vessels, and nerve endings.