ANATOMY

Detailed explanation-1: -Neutrophils, also known as polymorphonuclear leukocytes (PMNs), have long been considered as the short-lived, nonspecific white cells that form pus-and also happen to kill invading microbes.

Detailed explanation-2: -Neutrophils are the most abundant white blood cell in humans and arise from granulocytes. They are also phagocytic in nature, and Metchnikoff called neutrophils the “archetypal phagocyte”. Neutrophils are the first immune cells to be recruited, which can be through the cytokines produced by macrophages.

Detailed explanation-3: -Monocytes, macrophages, and neutrophils are phagocytes. A phagocyte is a type of white blood cell.

Detailed explanation-4: -The phagocyte’s membrane surrounds the pathogen and engulfs it in a vacuole . Enzymes found inside the cell then break down the pathogen in order to destroy it. As phagocytes do this to all pathogens that they encounter, they are called non-specific.

Detailed explanation-5: -Neutrophils are important effector cells in the innate arm of the immune system (Mayadas et al., 2014). They constantly patrol the organism for signs of microbial infections, and when found, these cells quickly respond to trap and kill the invading pathogens.