ANATOMY

Detailed explanation-1: -Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes. Structure of DNA. Most DNA is found inside the nucleus of a cell, where it forms the chromosomes. Chromosomes have proteins called histones that bind to DNA.

Detailed explanation-2: -Histones are proteins responsible for DNA packaging. The DNA wraps around the histones. Histones are positively charged proteins and hence can easily bind to negatively charged DNA. Histones are also involved in controlling the expression of genes.

Detailed explanation-3: -These histones are crucial for efficient packaging of DNA, as well as the replication and segregation of chromosomes themselves. Due to their affiliation with DNA, histones are important for successful cell replication, which takes place via the cell cycle.

Detailed explanation-4: -Histones are a family of small, positively charged proteins termed H1, H2A, H2B, H3, and H4 (Van Holde, 1988). DNA is negatively charged, due to the phosphate groups in its phosphate-sugar backbone, so histones bind with DNA very tightly.