ANATOMY

Detailed explanation-1: -Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Gastric chief cells secrete pepsin as an inactive zymogen called pepsinogen. Parietal cells within the stomach lining secrete hydrochloric acid that lowers the pH of the stomach. A low pH (1.5 to 2) activates pepsin.

Detailed explanation-2: -It breaks down proteins into smaller peptides and amino acids that can be easily absorbed in the small intestine. Specific cells within the gastric lining, known as chief cells, release pepsin in an inactive form, or zymogen form, called pepsinogen.

Detailed explanation-3: -Types of Digestive Enzymes Lipase (made in the pancreas; breaks down fats) Protease (made in the pancreas; breaks down proteins)

Detailed explanation-4: -Pepsin works its best in strong hydrochloric acid. But the similarity with the other enzymes pictured here refers to a second type of acid. The active site of the acid proteases rely on two acidic aspartate amino acids, which activate a water molecule and use it to cleave protein chains.

Detailed explanation-5: -The trypsinogen enters the small intestine through the common bile duct and is converted to active trypsin. This active trypsin acts with the other two principal digestive proteinases-pepsin and chymotrypsin-to break down dietary protein into peptides and amino acids.