ANATOMY

Detailed explanation-1: -The rests of Malassez are epithelial cell remnants derived from the epithelial root sheath of Hertwig. Once the sheath of Hertwig has initiated odontoblast differentiation and dentin formation, the epithelium breaks down to leave a network of cells surrounding the root surface – the rests of Malassez (Ten Cate 1994).

Detailed explanation-2: -The epithelial cell rests of Malassez (ERM) are odontogenic epithelial cells located within the periodontal ligament matrix. While their function is unknown, they may support tissue homeostasis and maintain periodontal ligament space or even contribute to periodontal regeneration.

Detailed explanation-3: -Hertwig’s Epithelial Root Sheath (HERS) was first discovered as a bi-layered cell sheath surrounding the roots of amphibian teeth (e.g. in Triturus and Salamandra)(Hertwig, 1874). HERS descends from the oral epithelium and the enamel organ to form a collar around the cervical part of the amphibian tooth root (Fig.

Detailed explanation-4: -Epithelial cell rests of Malassez (ERM) are quiescent epithelial remnants of the Hertwig’s epithelial root sheath (HERS) that are involved in the formation of tooth roots. ERM cells are unique epithelial cells that remain in periodontal tissues throughout adult life.