ANATOMY

Detailed explanation-1: -Kidney development proceeds in three sequential stages along the urogenital ridge in a rostro-caudal direction, forming first the pronephros, followed by the mesonephros, and finally the metanephric kidney at the caudal end of the urogenital ridge.

Detailed explanation-2: -The metanephros is derived from two key structures: the ureteric bud (UB), which branches from the nephric duct, and a region of spatially defined intermediate mesoderm termed the metanephric mesenchyme (MM). The nephric duct (ND), also referred to as the Wolffian duct, empties into the cloaca.

Detailed explanation-3: -Mesenchymal cells of the intermediate mesoderm condense around the metanephric diverticulum to form the metanephrogenic blastema (see Figure 1(c)).

Detailed explanation-4: -Metanephric blastema (or metanephrogenic blastema) is one of the two embryological structure that gives rise to the kidney, the other one being the ureteric bud.