ANATOMY

Detailed explanation-1: -Answer and Explanation: A signal molecule that binds to an intracellular receptor molecule are usually small, hydrophobic molecules. One of the most common classes of molecules which bind to intracellular receptors are hormone signal molecules.

Detailed explanation-2: -Intracellular messengers: cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate, calcium, phosphatidylinositols, nitric oxide (NO), and diacylglycerol.

Detailed explanation-3: -Binding of the hormone induces conformational change in the receptor; this causes dissociation of the HSP and reveals a nuclear localisation sequence (or NLS) which enables the hormone–receptor complex to pass through nuclear membrane pores into the nucleus.

Detailed explanation-4: -Integrins are receptors in the plasma membranes of cells. They are multisubunit transmembrane proteins. They have large extracellular domains, consisting of individually structured subdomains covalently linked by flexible linkers.