ANATOMY

Detailed explanation-1: -Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn’t occur.

Detailed explanation-2: -Gigantism happens when a child has high levels of growth hormone (GH) in their body, which causes them to grow very tall. It’s caused by a tumor (macroadenoma) on their pituitary gland.

Detailed explanation-3: -Causes of acromegaly Acromegaly happens because your pituitary gland (a pea-sized gland just below the brain) produces too much growth hormone. This is usually caused by a non-cancerous tumour in the pituitary gland called an adenoma.

Detailed explanation-4: -In humans, this condition is caused by over-production of growth hormone in childhood, resulting in people up to 2.7 m (9.0 ft) in height. It is a rare disorder resulting from increased levels of growth hormone before the fusion of the growth plate which usually occurs at some point soon after puberty.

Detailed explanation-5: -Gigantism is very similar to acromegaly. Acromegaly is also caused by excess growth hormone secretion however, this happens during adulthood rather than childhood. This means that height is normal as the growth plates have fused before the excess growth hormone secretion occurs.