ANATOMY

Detailed explanation-1: -The roles of growth hormone include influencing our height, and helping build our bones and muscles. Natural levels of growth hormone fluctuate during the day, seemingly influenced by physical activity. For example, levels rise when we exercise. Growth hormone levels increase during childhood and peak during puberty.

Detailed explanation-2: -The growth hormone/IGF-1 system stimulates both the bone-resorbing and bone-forming cells, but the dominant effect is on bone formation, thus resulting in an increase in bone mass. Thyroid hormones increase the energy production of all body cells, including bone cells.

Detailed explanation-3: -GH directly and through IGF-I stimulates osteoblast proliferation and activity, promoting bone formation. It also stimulates osteoclast differentiation and activity, promoting bone resorption. The result is an increase in the overall rate of bone remodeling, with a net effect of bone accumulation.

Detailed explanation-4: -Descriptions. Somatrem and somatropin are man-made versions of human growth hormone. Growth hormone is naturally produced by the pituitary gland and is necessary to stimulate growth in children.