ANATOMY

Detailed explanation-1: -In negative feedback systems, a stimulus causes the release of a substance whose effects then inhibit further release. In this way, the concentration of hormones in blood is maintained within a narrow range. For example, the anterior pituitary signals the thyroid to release thyroid hormones.

Detailed explanation-2: -For example, testosterone is part of a negative feedback mechanism that inhibits GnRH release by the hypothalamus and LH release by the pituitary. In addition, the Sertoli cells secrete a substance called inhibin, which prevents FSH release from the pituitary.

Detailed explanation-3: -Another example of negative feedback is the regulation of the blood calcium level. The parathyroid glands secrete parathyroid hormone, which regulates the level of calcium in the blood. If calcium decreases, the parathyroid glands sense the decrease and secrete more parathyroid hormone.

Detailed explanation-4: -The hormone feedback mechanism is defined as the mechanism that is used to maintain the hormone balance in the blood / body. The increase or decrease in the concentration of that hormone can sometimes stimulate and increase the secretion of that hormone or inhibit the secretion of the hormone. It’s called feedback.