ANATOMY

Detailed explanation-1: -Thyroid hormone-T3, T4. They bind to receptors within target cells. Mechanism of action of the lipid-soluble steroid hormones and thyroid hormones. hormone molecule diffuses from the blood, through interstitial fluid and crosses lipid bilayer of the plasma membrane and enters inside cell.

Detailed explanation-2: -Lipid-soluble hormones easily diffuse through the cell membrane. Steroid hormones are the most common circulating lipid-soluble hormones. Steroid hormones include: testosterone, estrogens, progesterone, aldosterone and cortisol.

Detailed explanation-3: -Steroid hormones and thyroid hormone are lipid soluble. All other amino acid–derived hormones are water soluble.

Detailed explanation-4: -hormones and insulin are major protein hormones, and testosterone and estrogen are major steroid hormones.