ANATOMY

Detailed explanation-1: -Hypothyroidism is when the thyroid gland does not produce enough thyroid hormones. An underactive thyroid gland can lead to weight gain, tiredness, and feeling cold constantly.

Detailed explanation-2: -Hypothyroidism is a common condition where the thyroid doesn’t create and release enough thyroid hormone into your bloodstream. This makes your metabolism slow down. Also called underactive thyroid, hypothyroidism can make you feel tired, gain weight and be unable to tolerate cold temperatures.

Detailed explanation-3: -Your hypothalamus releases thyrotropin-releasing hormone (TRH), which triggers your pituitary gland to release thyroid-stimulating hormone (TSH), which stimulates your thyroid to release T3 and T4.

Detailed explanation-4: -Congenital hypothyroidism is a partial or complete loss of function of the thyroid gland (hypothyroidism) that affects infants from birth (congenital).

Detailed explanation-5: -Thyroid hormones are essential for normal brain development. They influence neurogenesis, neuronal and glial cell differentiation and migration, synaptogenesis, and myelination.