ANATOMY

GENERAL ANATOMY

ENDOCRINE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Steroid hormones are ____ (check all that apply)
A
made from chains of amino acids
B
made from cholesterol
C
soluble in water
D
non-soluble in water
Explanation: 

Detailed explanation-1: -Like cholesterol, steroid hormones are not soluble in water (they are hydrophobic). Because blood is water-based, lipid-derived hormones must travel to their target cell bound to a transport protein.

Detailed explanation-2: -Steroid hormones are insoluble in water; they are carried by transport proteins in blood. As a result, they remain in circulation longer than peptide hormones.

Detailed explanation-3: -Structure of Steroid Molecules Unlike phospholipids and fats, steroids have a fused ring structure. Although they do not resemble the other lipids, they are grouped with them because they are also hydrophobic and insoluble in water.

Detailed explanation-4: -Because all steroid hormones are derived from cholesterol, they are not soluble in plasma and other body fluids.

Detailed explanation-5: -Steroid hormones estrogen and testosterone are non-polar and can pass through the lipid bilayer without binding to a membrane receptor. Nonpolar steroid hormones bind to special receptors in the cell cytoplasm. These receptors are modified and migrate to the cell nucleus where they activate transcription.

There is 1 question to complete.