ANATOMY

Detailed explanation-1: -Acromegaly is a rare condition where the body produces too much growth hormone, causing body tissues and bones to grow more quickly. Over time, this leads to abnormally large hands and feet, and a wide range of other symptoms. Acromegaly is usually diagnosed in adults aged 30 to 50, but it can affect people of any age.

Detailed explanation-2: -Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism.

Detailed explanation-3: -What is Acromegaly? Acromegaly is a hormonal disorder that leads to the abnormal growth of hands, feet and face as shown in the below image This disorder is mainly caused due to the excessive production of the Growth Hormone(GH) produced by the Pituitary gland.

Detailed explanation-4: -Gigantism occurs when growth hormone hypersecretion occurs before the fusion of the long bone epiphysis and is characterized by tall stature. Acromegaly occurs when GH hypersecretion occurs after the fusion of the epiphysis leading to large extremities and characteristic facies.

Detailed explanation-5: -Gigantism and acromegaly are usually caused by a pituitary adenoma that secretes excessive amounts of growth hormone (GH); rarely, they are caused by non-pituitary tumors that secrete growth hormone–releasing hormone (GHRH). Gigantism occurs if GH hypersecretion begins in childhood, before closure of the epiphyses.