ANATOMY

Detailed explanation-1: -Abstract. The secretion of glucagon by pancreatic -cells plays a critical role in the regulation of glycaemia. This hormone counteracts hypoglycaemia and opposes insulin actions by stimulating hepatic glucose synthesis and mobilization, thereby increasing blood glucose concentrations.

Detailed explanation-2: -Glucagon is a hormone that works with other hormones and bodily functions to control glucose levels in the blood. It comes from alpha cells found in the pancreas and is closely related to insulin-secreting beta cells, making it a crucial component that keeps the body’s blood glucose levels stable.

Detailed explanation-3: -The -cells secrete glucagon as a response to low blood glucose. The major function of glucagon is to release glucose from the glycogen stores in the liver.

Detailed explanation-4: -Alpha cells ( cells) are endocrine cells that are found in the Islets of Langerhans in the pancreas. Alpha cells secrete the peptide hormone glucagon in order to increase glucose levels in the blood stream. Pancreatic islets (islets of Langerhans).

Detailed explanation-5: -The cells make up 25% of the islets of Langerhans and secrete glucagon, a 29-amino-acid peptide, in response to hypoglycemia. The cells synthesize proglucagon which is then cleaved by a proprotein convertase to form glucagon. Glucagon restores blood glucose levels by mobilizing glucose primarily from the liver.