ANATOMY

Detailed explanation-1: -Too much cortisol can cause some of the hallmark signs of Cushing syndrome-a fatty hump between your shoulders, a rounded face, and pink or purple stretch marks on your skin. Cushing syndrome can also result in high blood pressure, bone loss and, on occasion, type 2 diabetes.

Detailed explanation-2: -Symptoms of Cushing’s syndrome One of the main signs is weight gain and more body fat, such as: increased fat on your chest and tummy, but slim arms and legs. a build-up of fat on the back of your neck and shoulders, known as a “buffalo hump"

Detailed explanation-3: -Cushing disease is a rare condition, only affecting 10 to 15 people per million every year. It is more common in women and occurs most often in people between the ages of 20 and 50. A pituitary adenoma is the most common cause of Cushing disease. An adenoma is a pituitary tumor that is almost always benign.

Detailed explanation-4: -Chronic stress and poor stress management can cause Cushing disease, as cortisol is the hormone we produce when we’re stressed. Similarly, panic disorders that cause your cortisol to rise regularly, can also cause Cushing disease.

Detailed explanation-5: -What is the difference between Cushing disease and Cushing syndrome? Cushing disease occurs when Cushing syndrome is caused by an ACTH-producing pituitary tumor, whereas Cushing syndrome is the set of symptoms that results when there is a surplus of cortisol in the body.