ANATOMY

Detailed explanation-1: -The hormone melatonin plays a role in the sleep-wake cycle. Natural levels of melatonin in the blood are highest at night. Some research suggests that melatonin supplements might be helpful in treating sleep disorders, such as delayed sleep phase. They also may provide some relief from insomnia and jet lag.

Detailed explanation-2: -Melatonin plays an important role in regulating human sleep. Administration of sustained-release or transdermal formulation melatonin reduces sleep latency, increases total sleep time, and improves sleep maintenance [12, 13].

Detailed explanation-3: -In humans, it is the main hormone synthesized and secreted by the pineal gland.