ANATOMY

Detailed explanation-1: -Pancreatitis, cystic fibrosis and other conditions that affect the pancreas cause exocrine pancreatic insufficiency (EPI). People with EPI don’t have enough pancreatic (digestive) enzymes to break down foods and absorb nutrients. It can lead to malnutrition.

Detailed explanation-2: -Some metabolic disorders develop during a person’s life. The most common is diabetes mellitus. Type 1 diabetes is an autoimmune problem-the body destroys the cells in the pancreas that make insulin. Insulin helps the body use glucose (sugar) in the body for energy.

Detailed explanation-3: -Patients with chronic pancreatitis may not have any symptoms. However, with ongoing destruction of the gland and loss of its function, symptoms of malabsorption may develop. Chronic pancreatitis can also manifest with abdominal pain, and diabetes.

Detailed explanation-4: -When the pancreas becomes inflamed and stays that way for years, eventually its cells stop working the way they should, including those that can cause EPI. Many things can lead to chronic pancreatitis, including heavy alcohol use, smoking, genetic problems, and autoimmune disorders.

Detailed explanation-5: -Metabolic syndrome is a cluster of conditions that occur together, increasing your risk of heart disease, stroke and type 2 diabetes. These conditions include increased blood pressure, high blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels.