ANATOMY

Detailed explanation-1: -Most lipid hormones are steroid hormones, which are usually ketones or alcohols and are insoluble in water. Steroid hormones (ending in ‘-ol’ or ‘-one’) include estradiol, testosterone, aldosterone, and cortisol.

Detailed explanation-2: -The main class of lipid-derived hormone is the steroids which are derived from cholesterol and the eicosanoids. Steroid hormones include testosterone, estrogen and cortisol. Testosterone and estrogen are important regulators of reproductive function, secreted by both the testes and the ovaries.

Detailed explanation-3: -Steroid hormones are synthesized from cholesterol in the gonads and adrenal gland. They can be broadly classified as glucocorticoids, mineralcorticoids, androgens, estrogens and progestagens. Steroid hormones are lipid soluble, allowing them to diffuse through the plasma membrane.

Detailed explanation-4: -Steroid hormones and thyroid hormone are lipid soluble. All other amino acid–derived hormones are water soluble. Hydrophobic hormones are able to diffuse through the membrane and interact with an intracellular receptor. In contrast, hydrophilic hormones must interact with cell membrane receptors.

Detailed explanation-5: -Steroid hormones are the most common circulating lipid-soluble hormones. Steroid hormones include: testosterone, estrogens, progesterone, aldosterone and cortisol. The majority of steroid molecules circulate in the blood bound to a globulin carrier molecule.