ANATOMY

Detailed explanation-1: -Acromegaly is a hormonal disorder that develops when your pituitary gland produces too much growth hormone during adulthood. When you have too much growth hormone, your bones increase in size. In childhood, this leads to increased height and is called gigantism. But in adulthood, a change in height doesn’t occur.

Detailed explanation-2: -The most common cause of gigantism is a benign (noncancerous) tumor on your child’s pituitary gland (a pituitary adenoma) that releases excess growth hormone (GH).

Detailed explanation-3: -Overproduction of growth hormone causes excessive growth. In children, the condition is called gigantism. In adults, it is called acromegaly.

Detailed explanation-4: -Hypersecretion of GH in childhood causes gigantism with potential clinical symptoms including accelerated growth velocity with tall stature, enlargement of the hands and feet, coarsening of facial features, and headaches. Most cases are caused by benign pituitary adenomas3, 4, 5).

Detailed explanation-5: -Gigantism is a serious condition that is nearly always caused by an adenoma, a tumor of the pituitary gland. Gigantism occurs in patients who had excessive growth hormone in childhood. The pituitary tumor cells secrete too much growth hormone (GH), leading to many changes in the body.