ANATOMY

Detailed explanation-1: -Antibodies, also known as immunoglobulins, are glycosylated protein molecules present on the surface of B cells (surface immunoglobulins) serving as antigen receptors (BCR), or are secreted into the extracellular space where they can bind and neutralize their target antigens (15).

Detailed explanation-2: -Immunoglobulins (Igs) are antigen-binding proteins produced by B cells. Igs contain two identical heavy (H) chains and two identical light (L) chains. Each H chain associates with an L chain to form an antigen-binding site so that each Ig is bivalent.

Detailed explanation-3: -B lymphocytes, also called B cells, create a type of protein called an antibody. These antibodies bind to pathogens or to foreign substances, such as toxins, to neutralize them.

Detailed explanation-4: -The B-cell receptor complex is made up of cell-surface immuno-globulin with one each of the invariant proteins Ig and Ig. The immunoglobulin recognizes and binds antigen but cannot itself generate a signal.

Detailed explanation-5: -The specific region on an antigen that an antibody recognizes and binds to is called the epitope, or antigenic determinant. An epitope is usually made up of a 5-8 amino acid long chain on the surface of the protein.