ANATOMY

Detailed explanation-1: -The inflammatory response increases the amount of blood flow to the site of injury to get more nutrients and white blood cells to an area in need. To increase blood flow to the area, the blood vessels get wider (dilate).

Detailed explanation-2: -A typical inflammatory response consists of four components: inflammatory inducers; the detecting sensors; downstream mediators; and the target tissues that are affected.

Detailed explanation-3: -Clinically, acute inflammation is characterized by 5 cardinal signs: rubor (redness), calor (increased heat), tumor (swelling), dolor (pain), and functio laesa (loss of function) (Figure 3-1).

Detailed explanation-4: -An early, if not immediate, response to tissue injury is acute inflammation. Immediately following an injury, vasoconstriction of blood vessels will occur to minimize blood loss. The amount of vasoconstriction is related to the amount of vascular injury, but it is usually brief.