ANATOMY

Detailed explanation-1: -The immune system produces antibodies against these antigens that enable it to destroy these harmful substances. When you have an autoimmune disorder, your immune system does not distinguish between healthy tissue and potentially harmful antigens.

Detailed explanation-2: -Autoimmunity is the presence of antibodies (which are made by B lymphocytes) and T lymphocytes directed against normal components of a person (autoantigens). These components are called autoantigens or self-antigens and typically consist of proteins (or proteins complexed to nucleic acids).

Detailed explanation-3: -Sometimes the body responds to its own tissue as though the tissue was a foreign substance, creating antibodies against the tissue and triggering reactions that cause normal cells to be destroyed. This is called an autoimmune response or autoimmune disease.

Detailed explanation-4: -Autoantibodies are antibodies (immune proteins) that mistakenly target and react with a person’s own tissues or organs. One or more autoantibodies may be produced when a person has an autoimmune disorder and their immune system fails to distinguish between “self” and “non-self.”

Detailed explanation-5: -Sometimes the immune system makes a mistake and attacks the body’s own tissues or organs. This is called autoimmunity. One example of an autoimmune disease is type 1 diabetes, in which the immune system destroys the cells in the pancreas that produce insulin.