ANATOMY

GENERAL ANATOMY

IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cytotoxic T cells and Helper T cells are able to identify antigens because they are presented on the ____ protein outside cells.
A
major histocompatibility complex (MHC)
B
voltage gated ion channels
C
sodium potassium pump
D
phospholipids
Explanation: 

Detailed explanation-1: -To be recognized by a T cell, the antigen must bind a protein called the Major histocompatibility complex (MHC). Cytotoxic T cells recognize antigen bound to MHC protein type 1. [2] MHC not only aid in T cell activation, but it also has a vital role in the maturation of T cells in the thymus.

Detailed explanation-2: -There are two main types of T-cells: Helper T-cells stimulate B-cells to make antibodies and help killer cells develop. Killer T-cells or cytotoxic T-cells directly kill cells that have already been infected by a foreign invader.

Detailed explanation-3: -T helper cells recognize viral peptides in association with class II MHC protein, usually on the surface of an antigen-presenting cell (APC). These interactions result in T helper cell activation, proliferation and differentiation, providing the affinity of binding is sufficiently high.

Detailed explanation-4: -Cytotoxic T cells, also known as Killer T cells, generally target cancer, virally infected, or damaged cells. Killer T cells respond to antigens by releasing cytotoxic granules that lead to apoptosis. Helper T cells help recruit B cells and other cells involved in the immune response by releasing cytokines.

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