ANATOMY

Detailed explanation-1: -Where capillary permeability is increased locally, either by damage to the vessel wall or by the action of histamine, a local swelling known as a weal is produced. If the hydrostatic pressure is increased, as in muscle tissue during exercise, the rate of formation of tissue fluid will be increased.

Detailed explanation-2: -The smaller blood vessels in areas of inflammation show an increase in permeability as manifested by an increase in the flow of fluid from the capillaries into the tissue spaces. This increase in permeability may also be shown by the localization and concentration of colloidal dyes.

Detailed explanation-3: -The inflammatory response increases the amount of blood flow to the site of injury to get more nutrients and white blood cells to an area in need. To increase blood flow to the area, the blood vessels get wider (dilate).

Detailed explanation-4: -Increased permeability of blood vessels after reversible electroporation is facilitated by alterations in endothelial cell-to-cell junctions.