ANATOMY

Detailed explanation-1: -Precursors of T cells migrate from the bone marrow and mature in the thymus. This process is similar to that for B cells, including the sequential rearrangement of antigen receptor gene segments.

Detailed explanation-2: -Thymus Gland: T Cells migrating to the Thymus gland from the bone marrow will undergo a process of selection to eliminate not only the weakest cells, but also those so strong that they may attack healthy tissue cells (autoimmunity).

Detailed explanation-3: -T cells migrate from the bone marrow to the thymus, a small gland located in the neck. Here, they mature and differentiate into different types of T cells, such as CD8+ T cells and CD4+ T cells.

Detailed explanation-4: -The primary parts of the immune system include the bone marrow and thymus. The bone marrow is extremely important to the immune system because all the body’s blood cells (including T and B lymphocytes) originate in the bone marrow. B lymphocytes remain in the marrow to mature, while T lymphocytes travel to the thymus.

Detailed explanation-5: -The thymus supports the differentiation of multiple distinct T cell subsets that play unique roles in the immune system. CD4 and CD8 / T cells, / T cells, NKT cells, Treg, and IEL all develop in and must leave the thymus to provide their functions elsewhere in the body.