ANATOMY

Detailed explanation-1: -Muscles are well-known for their role in movement, strength and energy. However, there is evidence suggesting a relationship between muscle and immune function as well. Muscles produce and release compounds which play an important role in the proliferation, activation and distribution of some immune cells.

Detailed explanation-2: -Answer and Explanation: The integumentary, digestive, skeletal and circulatory systems work with the immune system.

Detailed explanation-3: -Organs and tissues important to the proper functioning of the immune system include the thymus and bone marrow, lymph nodes and vessels, spleen, and skin.

Detailed explanation-4: -Primary lymphoid organs: These organs include the bone marrow and the thymus. They create special immune system cells called lymphocytes. Secondary lymphoid organs: These organs include the lymph nodes, the spleen, the tonsils and certain tissue in various mucous membrane layers in the body (for instance in the bowel).