ANATOMY

Detailed explanation-1: -Macrophages and neutrophils (phagocytes) are the front-line defenders in your body’s immune system. They seek out, ingest, and destroy pathogens and other debris through a process called phagocytosis.

Detailed explanation-2: -The phagocyte digests the ingested particle with hydrolytic enzymes, which are contained within membrane-enclosed sacs called lysosomes found within the cell.

Detailed explanation-3: -Neutrophils engulf microbes only as they move over them, in a ‘vacuum-cleaner’ type of behaviour. This context-dependent nature of phagocytosis by neutrophils should be of particular relevance to human infectious diseases, especially for the early phase of encounter with microbes new to the host.

Detailed explanation-4: -Phagocytosis is a critical part of the immune system. Several types of cells of the immune system perform phagocytosis, such as neutrophils, macrophages, dendritic cells, and B lymphocytes. The act of phagocytizing pathogenic or foreign particles allows cells of the immune system to know what they are fighting against.

Detailed explanation-5: -Phagocytes. Phagocytes are a type of white blood cell that use phagocytosis to engulf bacteria, foreign particles, and dying cells to protect the body.