ANATOMY

Detailed explanation-1: -Keratin, a protein inside skin cells, makes up the skin cells and, along with other proteins, sticks together to form this layer.

Detailed explanation-2: -Type VII collagen is the major component of anchoring fibrils, structures within basement membranes beneath stratified squamous epithelium thought to mediate the adherence of the epidermis to the dermis of human skin.

Detailed explanation-3: -Anatomy of the skin The area that anchors the epidermis to the dermis is called the dermal-epidermal junction. It is responsible for the exchange of oxygen, nutrients and waste products between the vascularised dermis and the avascular epidermis.

Detailed explanation-4: -Collagen is the fibrous structural protein that makes up the white fibres (collagen fibres) of skin, tendons, bones, cartilage, and all other connective tissues.

Detailed explanation-5: -Dermis and hypodermis The dermis consists of dense, fibrous connective tissue whose predominant connective tissue component is collagen. The texture of collagen fibers serves as the basis for recognizing two layers of dermis.