GENERAL ANATOMY
MUSCLE ANATOMY
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
M-Line
|
|
|
H-Zone
|
|
|
Z-Disc
|
|
|
A-Band
|
Detailed explanation-1: -Z-discs (Z-disk, Z-line, Z-band) delineate the lateral borders of sarcomeres and are the smallest functional units in striated muscle. The core of a Z-disc consists of actin filaments coming from adjacent sarcomeres which are crosslinked by actinin molecules [1].
Detailed explanation-2: -The actin filaments are attached at their plus ends to the Z disc, which includes the crosslinking protein -actinin. The myosin filaments are anchored at the M line in the middle of the sarcomere.
Detailed explanation-3: -Thus, many Z-disc proteins directly bind actin. Not surprisingly, filamin, a well-studied actin-binding protein localizes at the Z-disc where it binds actin through a conserved N-terminal ABD, composed of two CH domains.
Detailed explanation-4: -Actin filaments are attached to the Z-line.