ANATOMY

Detailed explanation-1: -Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally occurring neurotransmitter, into acetic acid and choline.

Detailed explanation-2: -The enzyme acetylcholine esterase breaks down the neurotransmitter acetylcholine, which is released at nerve and muscle junctions, in order to allow the muscle or organ to relax.

Detailed explanation-3: - Once acetylcholine has activated its receptor to transmit its signal, it needs to be broken down to prepare the synapse for the arrival of the next signal; this is accomplished by the enzyme acetylcholinesterase, which removes acetylcholine from the synapse by breaking it down into inactive fragments.

Detailed explanation-4: -Attacking Acetylcholinesterase Poisons and toxins that attack the enzyme cause acetylcholine to accumulate in the nerve synapse, paralyzing the muscle. Over the years, acetylcholinesterase has been attacked in many ways by natural enemies.

Detailed explanation-5: -Acetylcholinesterase is involved in the termination of impulse transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the central and peripheral nervous systems.