ANATOMY

Detailed explanation-1: -Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.

Detailed explanation-2: -Neurotransmitters are stored in synaptic vesicles and are released by fusion of these vesicles to the plasma membrane.

Detailed explanation-3: -For most of the small-molecule neurotransmitters, specific transporter proteins remove the transmitters (or their metabolites) from the synaptic cleft, ultimately delivering them back to the presynaptic terminal for reuse (see Figure 6.6A).