ANATOMY

GENERAL ANATOMY

NERVOUS SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Myelin is a lipid insulation produced by the ____
A
astrocytes
B
ependymal cells
C
microglia
D
oligodendrocytes
Explanation: 

Detailed explanation-1: -CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function-to promote efficient transmission of a nerve impulse along the axon.

Detailed explanation-2: -Myelin Lipids-Role of Lipids in Myelin The high lipid/protein ratio in myelin contributes to the close packing and tight organization of the myelin sheath through non-covalent interactions between lipids and myelin proteins [9].

Detailed explanation-3: -Yes, the oligodendrocytes produce myelin sheaths in the CNS and Schwann cells produce myelin sheaths in the PNS. However, one other thing of note: a single oligodendrocyte can myelinate multiple neuronal axons, while a single Schwann cell can only myelinate a single nueron’s axon.

Detailed explanation-4: -Myelin in situ has a water content of about 40%. The dry mass of both CNS and PNS myelin is characterized by a high proportion of lipid (70 to 85%) and, consequently, a low proportion of protein (15 to 30%). In contrast, most biological membranes have a higher ratio of proteins to lipids.

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