ANATOMY

Detailed explanation-1: -It’s just above your brainstem, leading down to where your skull meets your neck and connects to your spinal cord. Though the term “substantia nigra” refers to just one of these structures, you actually have two. They’re on either side of your midbrain, and each has a pars reticulata and a pars compacta .

Detailed explanation-2: -The substantia nigra (SN) is a midbrain dopaminergic nucleus which has a critical role in modulating motor movement and reward functions as part of the basal ganglia circuitry.

Detailed explanation-3: -The substantia nigra is a motor nucleus located in the basal ganglia of the midbrain.

Detailed explanation-4: -Although it is often referred to as one structure, there are actually two substantia nigrae, one on each side of the brainstem. They are situated in the anterior midbrain and mark the transition point of the tegmentum and cerebral peduncles.

Detailed explanation-5: -The substantia nigra is a paired structure of the midbrain. More specifically, it is located posterior to the crus cerebri.