ANATOMY

Detailed explanation-1: -Microglia are cells of myeloid origin that populate the CNS during early development and form the brain’s innate immune cell type. They perform homoeostatic activity in the normal CNS, a function associated with high motility of their ramified processes and their constant phagocytic clearance of cell debris.

Detailed explanation-2: -Astroglia are a class of neural cells (also known as astrocytes) of ectodermal, neuroepithelial origin that sustain homeostasis and provide for defense of the central nervous system (CNS) (FIGURE 1).

Detailed explanation-3: -These results suggested that astrocytes remove cell debris in order to protect surrounding healthy neurons from the toxic materials released by the dead and dying cells.

Detailed explanation-4: -Microglia. Microglia, the innate immune cells in the CNS, have two primary roles in the brain that are common to myelomonocytic innate immune cells in all mammalian organs: they fight off and phagocytize viruses, bacteria, and other foreign invaders, and they remove cellular debris to facilitate wound repair.

Detailed explanation-5: -Microglia–the brain’s immune cells–play a primary role in removing cellular debris from the brain.