ANATOMY

Detailed explanation-1: -At a chemical synapse, an action potential triggers the presynaptic neuron to release neurotransmitters. These molecules bind to receptors on the postsynaptic cell and make it more or less likely to fire an action potential.

Detailed explanation-2: -What generates a nerve impulse on the post-synaptic membrane? Neurotransmitter binding with receptor sites.

Detailed explanation-3: -The binding of neurotransmitters, either directly or indirectly, causes ion channels in the postsynaptic membrane to open or close (Figure 7.1). Typically, the resulting ion fluxes change the membrane potential of the postsynaptic cell, thus mediating the transfer of information across the synapse.

Detailed explanation-4: -When a neurotransmitter binds to a postsynaptic receptor ion channels will either open or close. The closing or opening of these ion channels will lead to either a cell membrane depolarizing or hyperpolarizing.

Detailed explanation-5: -The acetylcholine molecule binds to a G protein-coupled receptor, triggering a downstream response that leads to inhibition of muscle contraction.