ANATOMY

Detailed explanation-1: -Your skin is lined with millions of special cells called neurons. These cells are able to detect changes in the environment outside your body. The neurons then send signals to the brain, so that your brain can appropriately respond to the change.

Detailed explanation-2: -Receptors are groups of specialised cells. They detect a change in the environment (stimulus). In the nervous system this leads to an electrical impulse being made in response to the stimulus. Sense organs contain groups of receptors that respond to specific stimuli.

Detailed explanation-3: -Sensory nerves innervate the epidermis and dermis as well as the subcutaneous fatty tissue as a three-dimensional network (425, 881, 951). Most of the nerve fibers are found in the mid-dermis and the papillary dermis.

Detailed explanation-4: -Summary: Neurons in human skin perform advanced calculations, previously believed that only the brain could perform. A characteristic of neurons that extend into the skin and record touch, is that they branch in the skin so that each neuron reports touch from many highly-sensitive zones on the skin.

Detailed explanation-5: -The first step leading to perception of innocuous touch is activation of cutaneous sensory neurons called low-threshold mechanoreceptors (LTMRs).