ANATOMY

Detailed explanation-1: -As the disease progresses, the cartilage becomes completely worn down and the bone rubs on bone. Bony spurs usually develop around the margins of the joint. Part of the pain results from these bone spurs, which can restrict the joint’s movement as well.

Detailed explanation-2: -The use of a joint leads to wear and eventual degeneration of the cartilage that cover the bones where they meet in the joint. This loss of protective cartilage causes the joint inflammation known as osteoarthritis, as bone starts to rub directly against bone.

Detailed explanation-3: -If left untreated, articular cartilage injuries can lead to the development of osteoarthritis, a condition in which the articular cartilage wears away, exposing the underlying bone. Joint replacement surgery may be required to treat osteoarthritis.

Detailed explanation-4: -With OA, the cartilage within a joint begins to break down and the underlying bone begins to change. These changes usually develop slowly and get worse over time. OA can cause pain, stiffness, and swelling.