ANATOMY

Detailed explanation-1: -The epiphyseal growth plate is the main site of longitudinal growth of the long bones. At this site, cartilage is formed by the proliferation and hypertrophy of cells and synthesis of the typical extracellular matrix. The formed cartilage is then calcified, degraded, and replaced by osseous tissue.

Detailed explanation-2: -3 – Longitudinal Bone Growth: The epiphyseal plate is responsible for longitudinal bone growth. The proliferative zone is the next layer toward the diaphysis and contains stacks of slightly larger chondrocytes. It makes new chondrocytes (via mitosis) to replace those that die at the diaphyseal end of the plate.

Detailed explanation-3: -Growth in height is driven by elongation of long bones due to chondrogenesis at the epiphyseal plates, also known as the growth plate. This process results from chondrocyte proliferation, hypertrophy, and extracellular matrix secretion.

Detailed explanation-4: -Answer and Explanation: Bone growth in length is called interstitial growth, and bone growth in diameter (thickness) is called appositional growth. Interstitial growth mainly takes place on the hyaline cartilage at the epiphyseal plate that surrounds the ends of long bones.

Detailed explanation-5: -The growth plate, also known as the epiphyseal plate is a thin layer of cartilage that lies between the epiphyses and metaphyses, and is where the growth of long bones takes place.