ANATOMY

Detailed explanation-1: -Urea can be irritating to skin, eyes, and the respiratory tract. Repeated or prolonged contact with urea in fertilizer form on the skin may cause dermatitis. High concentrations in the blood can be damaging.

Detailed explanation-2: -Uremia is the result of toxins building up in your blood. It’s a sign of severe kidney dysfunction such as end-stage renal disease. Uremia is a serious medical condition. It can cause hormone imbalances, metabolic problems and even death.

Detailed explanation-3: -The urea cycle or ornithine cycle converts excess ammonia into urea in the mitochondria of liver cells. The urea forms, then enters the blood stream, is filtered by the kidneys and is ultimately excreted in the urine.

Detailed explanation-4: -When you eat proteins, the body breaks them down into amino acids. Ammonia is produced from leftover amino acids, and it must be removed from the body. The liver produces several chemicals (enzymes) that change ammonia into a form called urea, which the body can remove in the urine.