ANATOMY

Detailed explanation-1: -Acute kidney failure can occur when: You have a condition that slows blood flow to your kidneys. You experience direct damage to your kidneys. Your kidneys’ urine drainage tubes (ureters) become blocked and wastes can’t leave your body through your urine.

Detailed explanation-2: -Causes include diabetes, high blood pressure and acute kidney injuries.

Detailed explanation-3: -Prerenal acute renal failure is characterized by diminished renal blood flow (60 to 70 percent of cases). In intrinsic acute renal failure, there is damage to the renal parenchyma (25 to 40 percent of cases). Postrenal acute renal failure occurs because of urinary tract obstruction (5 to 10 percent of cases).

Detailed explanation-4: -The most common causes of nosocomial AKI are volume depletion, sepsis, heart diseases, polytrauma, liver diseases, and drug toxicity. AKI can also be of postrenal (obstructive) origin, or a result of renal diseases including glomerulonephritis, vasculitis, tubulointerstitial nephritis, and cholesterol embolism.