GENERAL ANATOMY
URINARY SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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As glomerular filtrate moves through the ascending loop of Henle, the filtrate becomes more dilute. Why?
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the ascending loop of Henle is permeable to water and ions
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the ascending loop of Henle is permeable to ions but impermeable to water
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the ascending loop of Henle is impermeable to water and ions
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the ascending loop of Henle is permeable to water but not to ions
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Explanation:
Detailed explanation-1: -The ascending limb is impermeable to water but allows transport of electrolytes actively or passively. Therefore, as the concentrated filtrate pass upward, it gets diluted due to the passage of electrolytes to the medullary fluid.
Detailed explanation-2: -The thin ascending limb is impermeable to water, due to it having no aquaporin channels. Na+ reabsorption occurs passively through epithelial Na+ (eNaC) channels and Chloride (Cl-) ions are reabsorbed in the thin ascending limb through Cl-channels.
Detailed explanation-3: -The ascending limb of Henle’s loop is impermeable to water but permeable to electrolytes. As a result, the filtrate gets diluted as it moves up the ascending limb of Henle’s loop.
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