ANATOMY

Detailed explanation-1: -Tubular reabsorption is the process that moves solutes and water out of the filtrate and back into your bloodstream.

Detailed explanation-2: -Proximal tubules are responsible for reabsorbing approximately 65% of filtered load and most, if not all, of filtered amino acids, glucose, solutes, and low molecular weight proteins. Proximal tubules also play a key role in regulating acid-base balance by reabsorbing approximately 80% of filtered bicarbonate.

Detailed explanation-3: -The nephrons work through a two-step process: the glomerulus filters your blood, and the tubule returns needed substances to your blood and removes wastes. Each nephron has a glomerulus to filter your blood and a tubule that returns needed substances to your blood and pulls out additional wastes.

Detailed explanation-4: -Proximal Convoluted Tubule Water and glucose follow sodium through the basolateral membrane via an osmotic gradient, in a process called co-transport. Approximately 2/3rds of water in the nephron and 100% of the glucose in the nephron are reabsorbed by cotransport in the proximal convoluted tubule.

Detailed explanation-5: -Under normal circumstances, up to 180 g/day of glucose is filtered by the renal glomerulus and virtually all of it is subsequently reabsorbed in the proximal convoluted tubule. This reabsorption is effected by two sodium-dependent glucose cotransporter (SGLT) proteins.