ANATOMY

Detailed explanation-1: -The descending limb of the loop of Henle is permeable to water. Water diffuses into the hyperosmolar medullary interstitium. The osmolarity can reach a maximum of 1200 mOsm/L at the tip of the medullary interstitium in antidiuresis. The ascending limb (where loop diuretics work) is impermeable to water.

Detailed explanation-2: -The descending limb of the nephron loop is relatively impermeable to solutes and freely permeable to water.

Detailed explanation-3: -The descending portion of the loop of Henle is extremely permeable to water and is less permeable to ions, therefore water is easily reabsorbed here and solutes are not readily reabsorbed.

Detailed explanation-4: -Answer and Explanation: The descending limb of the nephron loop is impermeable to water while the ascending limb of the nephron is permeable to water.

Detailed explanation-5: -1) Ascending limb of loop of Henle is impermeable to electrolytes, but is permeable to water.