ANATOMY

Detailed explanation-1: -Concentration of the filtrate primarily occurs in the collecting duct, and the distal convoluted tubule transports urine from the loop of Henle to the collecting duct. Filtration occurs in the glomerulus and Bowman’s capsule, know together as the renal corpuscle.

Detailed explanation-2: -As a result, the filtrate leaving the Bowman’s capsule is very similar to blood plasma (filtrate or glomerular filtrate is composed of blood plasma minus plasma protein i.e. it contains all the components of blood plasma except the proteins) in composition as it passes into the proximal convoluted tubule.

Detailed explanation-3: -Bowman’s capsule surrounds the glomerular capillary loops and participates in the filtration of blood from the glomerular capillaries. Bowman’s capsule also has a structural function and creates a urinary space through which filtrate can enter the nephron and pass to the proximal convoluted tubule.

Detailed explanation-4: -The colloidal pressure in the Bowman’s capsule is negligible because of the almost total absence of proteins. As a result, the effective filtration pressure is 10 to 15 mmHg (Navar et al., 1977). Figure 16-3. Pressures involved in glomerular filtration within a glomerular capillary.