ANATOMY

Detailed explanation-1: -The proximal convoluted tubule (PCT) is a segment of the renal tubule responsible for the reabsorption and secretion of various solutes and water. The PCT is located in the renal cortex, the outer part of the kidney, and is the first segment of the renal tubule, where it receives the filtrate from the renal corpuscle.

Detailed explanation-2: -Reabsorption is the movement of water and solutes from the tubule back into the plasma. Reabsorption of water and specific solutes occurs to varying degrees over the entire length of the renal tubule. Bulk reabsorption, which is not under hormonal control, occurs largely in the proximal tubule.

Detailed explanation-3: -Tubular reabsorption is the second major step in urine formation. Most of the reabsorption of solutes necessary for normal body function, such as amino acids, glucose, and salts, takes place in the proximal part of the tubule.

Detailed explanation-4: -The proximal convoluted tubule avidly reabsorbs filtered glucose into the peritubular capillaries so that it is all reabsorbed by the end of the proximal tubule.